Causes of Myasthenia Gravis


Myasthenia gravis is an autoimmune disease, an illness that develops when the person's body tissues are attacked by their own immune system. Immune system within the body is there to find and destroy foreign undesirable intruders, such as bacteria, toxins, or viruses. If somebody has an autoimmune disease their abnormal antibodies, which circulate in the blood, attack normal components of body tissues.

In Myasthenia gravis, antibodies are produced that block or destroy muscle receptor cells. Our nerves communicate with our muscles by releasing neurotransmitters (type of chemicals) which fit precisely into receptor sites on the muscle cells (muscle receptor cells). Blocking of these receptors leads to decrease in number of functional muscle fibers resulting inadequate communication between the nerves and affected muscles; the muscles then cannot contract properly and become tired and weak very easily - with fewer receptor sites the muscles receive fewer nerve signals.

Symptoms among patient who already have the disease may worsen with some medications, such as beta blockers, calcium channel blockers, quinine, and some antibiotics. Many believe some people have a genetic propensity to developing the disease.

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The following are known to make Myasthenia Gravis symptoms worse:

  • Emotional/mental stress
  • Illness
  • Some medications
  • Tiredness
  • Very high temperatures



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Myasthenia Gravis


Signs & Symptoms of Myasthenia


Diagnosing Myasthenia Gravis


Myasthenia gravis is an autoimmune disorder, in which antibodies circulating in the blood cause weakness by blocking


A symptom is something the patient feels and reports, while a sign is something other people, such as the doctor detect.


Patients who experience undue weakness which improves with rest have the hallmark signs of Myasthenia Gravis (MG) - it is a key sign.


Treatment options for Myasthenia


Complications of Myasthenia Gravis



There is no cure for myasthenia gravis. However, most therapies (treatments) are very effective in controlling symptoms.


Myasthenic crisis - the respiratory muscles become so weak that the patient cannot breathe properly. This is potentially


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License Number: U.P State Medical Council (India) No. 27637